The Next Unicorns E4 Alto CEO Matt Gamache-Asselin is fixing US pharmacy w/ aligned incentives | E980

Jason Calacanis talks with Mattieu Gamache-Asselin, discussing the transition from ScriptDash to Alto Pharmacy, their early days with Twitch founder Justin Kan, and how they're fixing broken pharmacies. They explore Alto's growth, the opioid crisis, and the importance of balancing aggression with medical regulations.

Speakers

AI Chat

Unidentified

Jason Calacanis

Host • 60%

Unidentified

Matt Gamache-Asselin

Guest • 36%

Unidentified

Chapters

0:00	Opening
0:51	Jason intros Mattieu Gamache-Asselin
2:52	Changing from ScriptDash to Alto Pharmacy
4:19	Meeting and working with Twitch founder Justin Kan in the early days of Alto
6:51	Message to HBO’s Silicon Valley writing room
7:26	Working out of Justin Kan’s house
8:15	Why are pharmacies broken? How is Alto fixing them?
14:25	How did Alto’s team architect a 1.0 version of their pharmacy?
21:44	US Healthcare is broken due to bad incentive structures
28:23	Does Alto compare to Hims and Roman?
32:24	What are Alto’s profit margins?
35:00	This Week in Cinema: It’s a Wonderful Life
39:07	Maintaining balance between being scrappy/aggressive while also abiding by all medical regulations
39:54	How has Alto scaled so far?
45:55	Who is responsible for the opioid crisis?
51:24	What is Alto building to combat the crisis?
53:27	Trading short-term gain for long-term gain
56:56	How Alto was initially received among investors
1:01:03	This Week in Cinema: The Mission
1:04:30	What skill does Matt think many founders lack?
1:07:02	Operational excellence in former Amazon executives
1:13:49	1 Lesson that Matt has learned since becoming a founder

Transcript

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